Synthesis, Physicochemical and Antimicrobial Studies of Schiffbase Ligand derived from Benzaldehyde and Urea and its Ni(II) and Cu(II) Metal Complexes

Ndahi *J. A.,   Mukhtar Haruna, A B. Mustapha and A. U. Modibbo

Department of Chemistry, Modibbo Adama University (MAU) Yola.

*Email:jipsy1965@gmail.com

ABSTRACT

Metal complexes of Ni (II) and Cu (II) with Schiff-base were successfully synthesized, characterized by solubility, melting point/decomposition temperature, molar conductivity, FT-IR, magnetic susceptibility, and elemental analysis. The complexes have a 1:2 metal-ligand ratio and low molar conductance values, indicating nonelectrolytes. They were tested for antibacterial activity against pseudomonas and Escherichia coli and Candida albicans and Aspergillus flavus. Both the free ligand and the complexes showed antibacterial activity, with higher activity at high concentrations. The complexes showed better antibacterial and fungal activity than the free ligand.

Keywords: Urea, Synthesis, Benzaldedyde, Microorganisms, Azomethine.

CITE AS: Ndahi J. A.,   Mukhtar Haruna, A B. Mustapha and A. U. Modibbo (2024). Synthesis, Physicochemical and Antimicrobial Studies of Schiffbase Ligand derived from Benzaldehyde and Urea and its Ni (II) and Cu (II) Metal Complexes. NEWPORT INTERNATIONAL JOURNAL OF PUBLIC HEALTH AND PHARMACY, 5(2): 50-56. https://doi.org/10.59298/NIJPP/2024/523945056