Global Health Partnerships in Action: Evaluating the Impact of WHO, UNAIDS, and the Global Fund on HIV/AIDS Prevention and Treatment in East Africa

Muhumuza Isaac

Department of Medicine and Surgery Kampala International University Uganda

Email: Isaac.muhumuza@studwc.kiu.ac.ug

                                                                     ABSTRACT
HIV/AIDS continues to pose a significant public health challenge in East Africa, disproportionately affecting young people, women, and marginalized populations, while straining already under-resourced health systems. This review evaluates the impact of global health partnerships specifically the World Health Organization (WHO), the Joint United Nations Programme on HIV/AIDS (UNAIDS), and the Global Fund, on HIV/AIDS prevention, treatment, and health system strengthening in the region. It examines their roles in expanding antiretroviral therapy (ART), promoting voluntary testing, preventing mother-to-child transmission, and integrating HIV services into primary healthcare. While these partnerships have achieved notable successes, persistent challenges remain, including donor dependency, inequitable access for key populations, and limitations of vertical program delivery. The review highlights the importance of sustainable, locally led strategies, integration of services, innovative digital and community-based approaches, and targeted interventions for marginalized groups. Findings underscore that effective collaboration between global and local actors is essential for resilient, equitable, and context-specific HIV/AIDS responses in East Africa.

Keywords: HIV/AIDS, East Africa, global health partnerships, WHO, UNAIDS, Global Fund.

CITE AS: Muhumuza Isaac. (2026). Global Health Partnerships in Action: Evaluating the Impact of WHO, UNAIDS, and the Global Fund on HIV/AIDS Prevention and Treatment in East Africa. NEWPORT INTERNATIONAL JOURNAL OF RESEARCH IN MEDICAL SCIENCES ,7(2):88-93 https://doi.org/10.59298/NIJRMS/2026/7.2.8893