Exploring the Biochemistry of Medicinal Plants in HIV and Diabetes Management

Taliikwa Nicholas Ceaser

Department of Pharmacognosy Kampala International University Uganda

Email:ceaser.taliikwa@studwc.kiu.ac.ug

ABSTRACT

The global burden of chronic diseases such as HIV/AIDS and diabetes mellitus necessitates the exploration of affordable and effective treatment alternatives. Medicinal plants, long recognized for their therapeutic value in traditional medicine, offer a promising avenue for the development of novel bioactive compounds with minimal side effects. This paper explores the biochemical composition of medicinal plants and their mechanisms of action in managing HIV and diabetes. It provides an overview of key plant-derived secondary metabolites such as alkaloids, flavonoids, saponins, and terpenoids that exhibit antiviral and antidiabetic activities. The integration of ethnomedicinal knowledge with biochemical and pharmacological research has led to the identification of plant-based inhibitors of HIV enzymes and phytochemicals capable of regulating glucose metabolism. Despite substantial progress, challenges persist in standardization, clinical validation, and equitable access. Future directions call for multidisciplinary collaboration to harness the full potential of these natural resources in combating these two major global health challenges.

Keywords: Medicinal Plants, HIV/AIDS, Diabetes Mellitus, Phytochemicals, Bioactive Compounds, Antiretroviral Therapy, Insulin Resistance, Traditional Medicine.

CITE AS: Taliikwa Nicholas Ceaser (2025). Exploring the Biochemistry of Medicinal Plants in HIV and Diabetes Management. NEWPORT INTERNATIONAL   JOURNAL OF SCIENTIFIC AND   EXPERIMENTAL SCIENCES 6(3):80-89 https://doi.org/10.59298/NIJSES/2025/63.8089