Quantitative Phyto-evaluation and Antimicrobial studies of the n-butanol stem bark fraction of Detarium microcarpum

                     ¹ M.H Shagal, ²D. Abubakar. ³ I.I Nkafamiya and ⁴A. M. Fulata

^1,2,3 Department of Chemistry, Adamawa state, Nigeria Modibbo Adama University Yola

⁴Federal Polytechnic Monguno, Borno State, Nigeria

ABSTRACT

This paper examines the phytochemical constituents and antimicrobial efficacies of n-butanol stem bark fraction of Detarium microcarpum using an in vitro model. The results revealed that the N-butanol fraction of Detarium microcarpum stems tested positive for the presence of Alkaloids, Saponins, Tannins, Flavonoids, Anthraquinones, steroids, and Glycosides. Similarly, the in vitro antimicrobial study also revealed that the n-butanol fraction has effectively inhibited the growth of test organism’s pathogens (Protius, Bacillus subtilis, staphylococaccus aureus, Enterobacta, Eschericia coli, Shigelia dysenteriae, Salmonella typhi, Pseudomonas aeruginosa, Aspergillus nigger. Aspergillus flavus, Candida albicans, Rhezome). The minimum Inhibitory Concentration (MIC).  Range from 1.0×10⁴ to 4.0×10^4.

Keywords: Phytochemical Analysis, Antimicrobial Activity, Detarium microcarpum, n-Butanol Fraction, Minimum Inhibitory Concentration (MIC)

CITE AS: M.H Shagal, D. Abubakar, I.I Nkafamiya and A. M. Fulata (2024).Quantitative Phyto-evaluation and Antimicrobial studies of the n-butanol stem bark fraction of Detarium microcarpum. NEWPORT INTERNATIONAL JOURNAL OF BIOLOGICAL AND APPLIED SCIENCES, 5 (1):92-96. https://doi.org/10.59298/NIJBAS/2024/5.1.9296118